ColdZyme Mouth & Throat Spray (Not Nasal Spray) - Cold Virus Treatment & Symptom Relief - Use at First Signs of a Cold - Menthol Flavour 20ml

Product Information

In the event of any safety concerns or for any other information about a product please carefully read any instructions provided on the label or packaging and contact the manufacturer. The participants received a weekly electronic survey for 3 months, where they retrospectively reported the common colds that they experienced during the previous week and graded the average daily severity of the cold using the Jackson rating scale [13] and a visual-analogue scale (VAS) graded from 0 (mildest possible cold) to 100 (worst possible cold). ColdZyme ® is intended to be used against colds during virus exposure and can shorten the cold if used early in the course of the disease. The aim of the study was to evaluate the efficacy of ColdZyme for common cold, with the study hypothesis that treatment with ColdZyme is superior to placebo in the treatment of naturally occurring common cold.

on a visual-analogue scale (VAS) ranging from 0 (mildest possible cold) to 100 (worst possible cold). Jackson’s symptom scale and the 9-item Wisconsin Upper Respiratory Symptom Survey-21 (WURSS-21) quality of life (QoL) domain and a sore throat scale were recorded daily by subjects, as well as any use of allowed rescue treatment. Early self-diagnosis and early use of ColdZyme mouth spray is a safe alternative for treatment of naturally occurring colds. Lastly, the experimental design of this trial did not include a concomitant untreated group, nor was virus presence or type confirmed.ColdZyme® is easy to use and acts immediately by forming a protective barrier in the oral cavity and throat. Early self-diagnosis and use of the medical device ColdZyme indicate a safe alternative for treatment in naturally occurring common colds.

Men and women (18–70 years) with at least three occurrences of common cold within the previous 12 months, but otherwise in good health and willing to comply with the trial procedures, were eligible and screened for enrolment at the study sites against inclusion and exclusion criteria.

If the last value of the period was missing, it was imputed by the subject’s last available value before (LOCF approach); subsequent values after the period (e. R. have provided consultancy services and have received payment from Enzymatica AB for services rendered. Ideal for those who can't afford to be ill, whether you're an athlete in training, a busy commuter or a parent dealing with viruses picked up at school. To prevent infection, the natural barrier can be strengthened by depositing a barrier to the oropharyngeal mucous membrane.

Those randomized to the ColdZyme group received the investigational device, a throat spray consisting of glycerol, water, trypsin secreted from the pyloric caeca of the Atlantic cod, ethanol (<1%), calcium chloride, trometamol and menthol (ColdZyme ®, Enzymatica, Sweden). The medication contains proteins that can kill the virus before it can enter cells, reducing the chance of it causing any damage. for the placebo group on the evening of Day 1, which was similar to the previous single-blind trial (7. Children are the group who catch colds most often – 7 to 10 colds per year 3 – but this frequency declines with age.Exercise, Immune Function and Respiratory Infection: An Update on the Influence of Training and Environmental Stress. Epithelial cell layers in oral and nasal cavities form a physical and innate immune barrier against bacteria and viruses [9] . The enzyme is extracted as a by-product in the preparation of cod and therefore does not burden the marine ecosystem.